Engage in epic battles against microscopic foes in 'STEM Defense', a strategic tower defense adventure set on a hex-grid. Harness the immune system's power, BUILD your defenses and fend off waves of pathogens, unlock potent cells and upgrades, and evolve your defenses for a grand survival showdown!
We are not affiliated with IsThereAnyDeal.































Iimmerses yourself in a strategic battle within the human body, where you manipulate pathways and tower placements on a dynamic hexagonal grid. This educational tower defense game teaches players about the immune system through engaging gameplay, focusing on the defense against microscopic invaders.
Path Expansion: Dynamically extend the pathways pathogens travel to strategically shape each level and increase the effectiveness of your defenses.
Tower Placement Strategy: Strategic placement of your towers is essential. Elevate your towers to gain damage bonuses, crucial for optimizing defense effectiveness.
Mutation-Based Upgrades: Enhance your defenses through epigenetic modifications, providing temporary boosts, and genetic mutations for permanent enhancements. This mirrors real-life biological defense mechanisms.
Experience and Genetic Enhancements: Gain experience to unlock advanced defensive capabilities and permanent genetic upgrades, enhancing your ability to combat pathogens.
Varied Enemy Types: Encounter diverse pathogens, each with unique abilities. Develop strategies to handle enemies that can regenerate, accelerate, or spawn additional threats.
Endless Replayability: With a multitude of genetic enhancements and adaptive enemy tactics, each game offers new challenges and decisions, ensuring unique experiences with every playthrough.
Coming Soon: Acquired immunity mechanics!! Support Independent Development As a solo developer not well-versed in the art of social media, I rely on the support of players like you. If you've enjoyed "STEM Defense", please help spread the word and make it known to others!
Steam data © 2025 Valve Corporation. Steam and the Steam logo are trademarks and/or registered trademarks of Valve Corporation in the U.S. and/or other countries. Independent of Valve. Pricing and availability subject to change.































Iimmerses yourself in a strategic battle within the human body, where you manipulate pathways and tower placements on a dynamic hexagonal grid. This educational tower defense game teaches players about the immune system through engaging gameplay, focusing on the defense against microscopic invaders.
Path Expansion: Dynamically extend the pathways pathogens travel to strategically shape each level and increase the effectiveness of your defenses.
Tower Placement Strategy: Strategic placement of your towers is essential. Elevate your towers to gain damage bonuses, crucial for optimizing defense effectiveness.
Mutation-Based Upgrades: Enhance your defenses through epigenetic modifications, providing temporary boosts, and genetic mutations for permanent enhancements. This mirrors real-life biological defense mechanisms.
Experience and Genetic Enhancements: Gain experience to unlock advanced defensive capabilities and permanent genetic upgrades, enhancing your ability to combat pathogens.
Varied Enemy Types: Encounter diverse pathogens, each with unique abilities. Develop strategies to handle enemies that can regenerate, accelerate, or spawn additional threats.
Endless Replayability: With a multitude of genetic enhancements and adaptive enemy tactics, each game offers new challenges and decisions, ensuring unique experiences with every playthrough.
Coming Soon: Acquired immunity mechanics!! Support Independent Development As a solo developer not well-versed in the art of social media, I rely on the support of players like you. If you've enjoyed "STEM Defense", please help spread the word and make it known to others!
Engage in epic battles against microscopic foes in 'STEM Defense', a strategic tower defense adventure set on a hex-grid. Harness the immune system's power, BUILD your defenses and fend off waves of pathogens, unlock potent cells and upgrades, and evolve your defenses for a grand survival showdown!
We are not affiliated with IsThereAnyDeal.
Steam data © 2025 Valve Corporation. Steam and the Steam logo are trademarks and/or registered trademarks of Valve Corporation in the U.S. and/or other countries. Independent of Valve. Pricing and availability subject to change.