SIDE EFFECTS screenshot 1
SIDE EFFECTS - Release Trailer
SIDE EFFECTS - Announcement Trailer
SIDE EFFECTS Demo Trailer
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Nov 21, 2025·Mr.Pootsley·
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A twisted trial of pill roulette for up to 4 players (solo or online). Pick your poison. Use experimental items to shift the odds. And remember: only one of you can survive.

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About SIDE EFFECTS

Up to four test subjects. One twisted medical trial. Only one leaves.

SIDE EFFECTS video 1

Welcome to Side Effects: a tense, turn-based medical roulette game. Each round you'll be presented with a selection of pills. Some are helpful, some are harmful, and some mean instant death. You never know what you're about to consume or what it might do to your mind or body. Winning means outlasting – AKA, outliving – your opponent across the table.

SIDE EFFECTS video 2

Resist

Every pill impacts your resistance. Manage it wisely: zero resistance means death.

Experiment

Between rounds, you can choose from a range of experimental items and treatments that can shift the odds in your favor, from vaccines to mouth clamps.

You’re not alone

The other patient wants to outlast you. They’ll bluff, adapt, and use everything at their disposal to keep breathing one dose longer than you.

Would you like to participate?

SIDE EFFECTS video 3

This trial includes:

A single player mode
A multiplayer mode (2-4 Players)
15+ unique items
6 pill types to test

Steam data © 2026 Valve Corporation. Trademarks are property of their respective owners.

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