Immunica screenshot 1
Immunica - Announcement Trailer
Immunica screenshot 3
Immunica screenshot 4
Immunica screenshot 5
Immunica screenshot 6
Immunica screenshot 7
Immunica screenshot 8

Games Like Immunica

Mar 29, 2026·eranboi·
View on SteamBuyChecking stores…

Become the immune system. Hover to kill. Weapons fire automatically. Manage your research lab, hire scientists, and develop a vaccine while fighting off endless pathogen hordes.

Top matches

Match strength key:80+65+50+<50
Finding similar games…

About Immunica

In Immunica, YOU are the immune system. Pathogens are flooding in. Your health is dropping. Every second counts.

Control the immune system from within. No clicking required. Just move, position, and watch the chaos unfold as your weapons automatically tear through waves of invaders.

Immunica video 1

ACTIVE SURVIVAL + IDLE PROGRESSION

Hover over enemies to deal damage. Your cursor is your primary weapon. Meanwhile, missiles lock on, beams fire, drones orbit, and burst pulses detonate around you. Focus on positioning while your arsenal handles the rest.

Immunica video 2

4 WEAPON SYSTEMS

Burst - AOE pulse centered on your cursor
Missiles - Homing projectiles that hunt down targets
Beam - High-damage laser for focused destruction
Drones - Orbiting allies that intercept incoming threats
Immunica video 3

FEVER MODE

Chain kills to build your Fever meter. When it fills, unleash devastating power: up to +500% damage across 5 escalating tiers. The more you kill, the stronger you become.

Immunica video 4

40+ PATHOGEN SPECIES

Face 8 pathogen types across multiple tiers. From tiny Prions to massive Helminths, each species brings unique behavior patterns. Every pathogen has 3 evolution levels: Normal, Mutant, and Alpha. Higher tiers mean deadlier enemies and greater rewards.

Immunica video 5

RESEARCH LAB

Between breaches, manage your own research laboratory. Collect pathogen samples from combat and assign them to your scientists. Hire interns, technicians, researchers, and senior scientists. Each has different processing speeds, efficiency rates, and capabilities. Watch your team analyze samples even while you are away. Progress continues offline for up to 8 hours.

Your goal: accumulate enough Vaccine Data to complete the cure.

Immunica video 6

DEEP UPGRADE SYSTEM

Over 200 upgrades across multiple categories. Improve your cursor damage, fire rate, and critical chance. Unlock weapon systems and enhance their power. Strengthen your core health and damage resistance. Every protein spent makes you permanently stronger.

Immunica video 7

BREACH MODIFIERS

Each run randomly selects 1-3 modifiers from 30 possibilities:

Buffs - Advantages that boost your power
Nerfs - Increased difficulty with bonus protein rewards
Weird - Strange effects that completely change how the game plays

KEY FEATURES

Satisfying incremental progression that persists across runs
Active cursor gameplay combined with automated weapons
Idle lab management with offline progression
40+ pathogen species with 3 evolution levels each
30 breach modifiers for endless variety
Hidden synergies to discover through gameplay
Work toward a final goal: completing the vaccine

Steam data © 2026 Valve Corporation. Trademarks are property of their respective owners.

All matches

Similar games to Immunica

Finding similar games…