The Last Leukocyte: Immune Protocol screenshot 1
The Last Leukocyte: Immune Protocol - Announcement Trailer
The Last Leukocyte: Immune Protocol screenshot 3
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Fight cancer as the last leukocyte in a survivors-like action roguelite. Build your loadout with manual and automatic weapons, perks, and items while surviving in a living ecosystem that reacts to your presence and feeds on the remains of the dead.

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About The Last Leukocyte: Immune Protocol

You are the last leukocyte.

Stand against cancer as the final line of defense in a survivors-like action game set inside a living, hostile ecosystem.

You are not fighting through scripted waves or fixed timers. The world reacts to your presence as an unwanted intruder, and survival depends on how you move, fight, and disrupt the balance around you.

The Last Leukocyte: Immune Protocol video 1

A world that reacts to your actions.

The ecosystem does not exist just as a backdrop — it responds to what you do.

Absorb the remains of fallen enemies to grow stronger, but be careful: you are not the only organism feeding on the dead. The same resources that fuel your build can also strengthen other creatures, forcing you to choose between pushing forward, securing resources, or preventing the ecosystem from becoming even more dangerous.

The Last Leukocyte: Immune Protocol video 2

Build around weapons, items, and synergies.

Fight cancer with a mix of manual and automatic firepower.

Use 2 manual weapons that you control directly and 2 automatic weapons that support your build in different ways. Some automatic weapons fire constantly, while others activate during reload windows, turning timing, weapon management, and positioning into core parts of combat.

Unlock perks, collect items, and create powerful synergies. In The Last Leukocyte: Immune Protocol, every mechanic is meant to matter.

The Last Leukocyte: Immune Protocol video 3

Adapt to a living battlefield.

Face a growing biological threat and shape your build against an ecosystem full of enemies with different roles and behaviors.

20+ different enemies, each fulfilling its own role
15+ perks
25+ weapons
30+ itemsSurvive escalating encounters, grow stronger during each run, and push back against an ecosystem that evolves in response to your actions.

Steam data © 2026 Valve Corporation. Trademarks are property of their respective owners.

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