Games Like Immunity Protocol

About Immunity Protocol

Immunity Protocol is a neon pixel-art horde-survival auto-shooter set inside a collapsing biotech system.

Deploy a combat sentinel into a living machine gone hostile. Drift through bloodstream channels, corrupted circuitry, synaptic architecture, and fiber-optic kill zones while swarms, elites, roaming hazards, and recurring boss breaches keep tightening the screen around you. You move. Your arsenal fires automatically. Survival depends on positioning, routing, and building something strong enough to outlast the collapse.

Core Features

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Manual movement, automatic fire Steer through dense enemy pressure while your build handles the shooting.

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10 playable sentinel chassis Start each run with a distinct weapon, passive identity, and combat style.

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6 symbiote companions Bring a support organism into battle for tanking, artillery, suppression, shielding, healing, or utility.

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Build-driven survival runs Draft weapons, passives, legends, and run-only augments as the run mutates under pressure.

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2 deployment zones, 4 biome identities Fight across bloodstream tissue, motherboard corridors, cerebral structures, and fiber-optic lanes with different traversal and encounter reads.

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Recurring bosses and live hazards Survive elite spikes, roaming environmental threats, and biome-routed boss encounters that keep changing the tempo of the run.

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Persistent laboratory progression Archive fragments, secure blueprints, unlock chassis upgrades, expand symbiosis options, and earn achievement bonuses between deployments.

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Readable neon pixel combat High-contrast visuals keep threats, rewards, hazards, and projectiles legible even when the screen turns chaotic.

At Launch Includes

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10 playable sentinel chassis

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27 weapons

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17 passive upgrades

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6 symbiote companions

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2 deployment zones across 4 biome identities

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10 biome-routed bosses

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12 achievements with permanent bonuses

Optional AI Windows Hardware Feature On supported Windows systems, Immunity Protocol can enable optional AI-assisted combat behaviors on verified NPU hardware, including enemy tactics, pressure-direction support, and reward recommendations. This feature is verified-hardware only, is not required to play, and the full game remains fully playable without AI augmentation. The Linux release does not include this optional verified NPU path.

Survive the breach. Rewrite the immune response!